RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-29b-1
RNA ID
RNA Type
miRNA
Alteration Pattern
dna methylation;down regelation
Species
homo sapiens
Detection Methods
qRT-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
PTEN
Pathway
PTEN
PubMed ID
Title
Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis
Year
2014
Function
Dna methylation and mecp2 may provide molecular mechanisms for silencing of ptch1.